Comparison of Nerve Fiber Density between Patients with Uterine Leiomyoma with and without Pain: a Prospective Clinical Study
| Autor: | Ayşegül Türkgeldi, Esra Esim-Buyukbayrak, Sevinc Hallac-Keser, Ayse Yasemin Karageyim-Karsidag, Burak Giray |
|---|---|
| Přispěvatelé: | Giray, Burak, Esim-Buyukbayrak, Esra, Hallac-Keser, Sevinc, Karageyim-Karsidag, Ayse Yasemin, Turkgeldi, Aysegul |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Visual analogue scale medicine.medical_treatment Urology Nerve fiber neurofilament DIAGNOSIS Protein-Genprodukt 9.5 MYOMETRIUM 03 medical and health sciences Beckenschmerzen 0302 clinical medicine Leiomyom des Uterus Maternity and Midwifery Medicine GebFra Science Nervenfasern INNERVATION 030219 obstetrics & reproductive medicine Uterine leiomyoma Hysterectomy uterine leiomyoma business.industry nerve fibers Pelvic pain ENDOMETRIOSIS protein gene product 9.5 WOMEN Obstetrics and Gynecology pelvic pain medicine.disease female genital diseases and pregnancy complications ESTROGEN Leiomyoma medicine.anatomical_structure 030220 oncology & carcinogenesis FIBROIDS Prospective clinical study HYSTERECTOMY Immunohistochemistry Original Article medicine.symptom business |
| Zdroj: | Geburtshilfe und Frauenheilkunde |
| ISSN: | 1438-8804 0016-5751 |
| DOI: | 10.1055/a-0591-1751 |
| Popis: | Introduction We aimed to compare the presence and the amount of nerve fibers in endometrial, myometrial and leiomyoma tissues using protein gene product 9.5 (PGP 9.5) and neurofilament (NF) immunohistochemical staining in uterine leiomyoma patients with and without pain complaint. Methods Patients undergoing hysterectomy for uterine leiomyoma were prospectively enrolled in the study. Twenty-five uterine leiomyoma patients without pelvic pain complaint (visual analog scale (VAS) Results None of the endometrial samples in either groups stained with PGP 9.5 and NF dyes. There was no statistically significant difference in the number of nerve fibers in myometrial and leiomyoma tissues between the two groups with either of the stains (PGP 9.5: p = 0.39 and p = 0.29; NF: p = 0.83 and p = 0.65, respectively). There was agreement between PGP 9.5 and NF immunohistochemical staining for nerve fiber detection in myometrial and leiomyoma tissues (p Conclusion This study demonstrates that the quantity and density of nerve fibers in myometrial and leiomyoma tissue in patients with pain were similar to that in patients without pain. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|