Probabilistic sequence learning in mild cognitive impairment
| Autor: | Dezso Nemeth, Karolina Janacsek, Zsuzsa Londe, Kata Fazekas, Katalin Király, Kornél Németh, Ilona Adam, Király Elemérné, Attila Csányi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Serial reaction time
medicine.medical_specialty education BF Automaticity Audiology automaticity Hippocampus lcsh:RC321-571 Developmental psychology Task (project management) Behavioral Neuroscience mild cognitive impairment medicine Original Research Article lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Biological Psychiatry offline learning sequence learning Recall Probabilistic logic Implicit learning Psychiatry and Mental health statistical learning Neuropsychology and Physiological Psychology Neurology Offline learning Sequence learning skill learning Psychology implicit learning consolidation Neuroscience |
| Zdroj: | Frontiers in Human Neuroscience Frontiers in Human Neuroscience, Vol 7 (2013) Frontiers in human neuroscience |
| ISSN: | 1662-5161 |
| Popis: | Mild Cognitive Impairment (MCI) causes slight but noticeable disruption in cognitive systems, primarily executive and memory functions. However, it is not clear if the development of sequence learning is affected by an impaired cognitive system and, if so, how. The goal of our study was to investigate the development of probabilistic sequence learning, from the initial acquisition to consolidation, in MCI and healthy elderly control groups. We used the Alternating Serial Reaction Time task (ASRT) to measure probabilistic sequence learning. Individuals with MCI showed weaker learning performance than the healthy elderly group. However, using the reaction times only from the second half of each learning block – after the reactivation phase - we found intact learning in MCI. Based on the assumption that the first part of each learning block is related to reactivation/recall processes, we suggest that these processes are affected in MCI. The 24-hour offline period showed no effect on sequence-specific learning in either group but did on general skill learning: the healthy elderly group showed offline improvement in general reaction times while individuals with MCI did not. Our findings deepen our understanding regarding the underlying mechanisms and time course of sequence acquisition and consolidation. |
| Databáze: | OpenAIRE |
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