One-year endurance training: Effects on lung function and airway inflammation
| Autor: | Helmi Ben Saad, Myriam Denguezli, Abdelkrim Zbidi, Zouhaier Tabka, Imen Ben Chiekh, Monia Zaouali-Ajina |
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| Rok vydání: | 2008 |
| Předmět: |
Lung Diseases
Male Neutrophils Physiology Physical Therapy Sports Therapy and Rehabilitation Running Pulmonary function testing chemistry.chemical_compound Endurance training Surveys and Questionnaires medicine Humans Macrophage Orthopedics and Sports Medicine Respiratory system Lung Inflammation Analysis of Variance Leukotriene E4 Exercise Tolerance business.industry Macrophages Sputum Respiratory Function Tests chemistry Spirometry Immunology Exercise Test Physical Endurance medicine.symptom business Airway Biomarkers Histamine |
| Zdroj: | Journal of Sports Sciences. 26:1351-1359 |
| ISSN: | 1466-447X 0264-0414 |
| DOI: | 10.1080/02640410802123177 |
| Popis: | The aim of this study was to determine whether endurance training in athletes induces airway inflammation and pulmonary function disorders. Respiratory pattern and function were analysed in ten healthy endurance runners at rest, during sub-maximal exercise, and during the recovery. Inflammatory cells and metabolites (histamine, interleukin-8, and leukotriene E(4)) were measured in sputum at rest and after exercise. The experiments were conducted on three different occasions (basic endurance training, pre-competitive and competitive periods). In spite of the absence of post-exercise spirometric changes and respiratory symptoms, airway cells counts and inflammatory markers changed significantly. At the beginning of the experiment, athletes' induced sputum showed an abundance of macrophages compared with neutrophils. We found a high percentage of neutrophils during the pre-competitive and competitive periods of the sport season (41% and 37%), a significant increase in macrophage counts during the pre-competitive period (51%), and a significant rise in total cells, interleukin-8, leukotriene E(4), and histamine during the competitive period. In conclusion, one year's training increased markers of inflammation in the airways of endurance runners without symptoms or changes in pulmonary function, suggesting that airway inflammation is of insufficient magnitude to markedly impact lung function in healthy athletes. |
| Databáze: | OpenAIRE |
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