Survey of Australasian Renal and Rheumatology Specialists investigating topical NSAID use and adverse renal outcomes
| Autor: | Vikas Srivastava, Matthew Terrill, Muriel Soden |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
musculoskeletal diseases
Nephrology Musculoskeletal pain medicine.medical_specialty Nursing (miscellaneous) Physical Therapy Sports Therapy and Rehabilitation Osteoarthritis urologic and male genital diseases Kidney 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine Surveys and Questionnaires Medicine Humans Orthopedics and Sports Medicine 030212 general & internal medicine skin and connective tissue diseases 030203 arthritis & rheumatology business.industry Rehabilitation Anti-Inflammatory Agents Non-Steroidal Australia medicine.disease Chiropractics business |
| Zdroj: | Musculoskeletal careREFERENCES. 18(2) |
| ISSN: | 1557-0681 |
| Popis: | A survey investigated physician reported use, prescribing practices and adverse renal events of topical NSAIDs.This survey was sent to members of the Australian Rheumatology Association and the Australian and New Zealand Society of Nephrology.Sixty physicians responded, 55% (n = 33) were nephrologists; 45% (n = 27) rheumatologists. Nearly all (n = 56, 93.3%) had managed at least one patient using topical NSAIDs, including those with an eGFR45 mL/min (n = 55, 91.7%). Concern was expressed that patients may use topical NSAIDs without the physician's knowledge. The majority (n = 40, 66.6%) have prescribed (or recommended) a topical NSAID, slightly less in patients with a reduced eGFR45 mL/min (n = 36, 60.0%). Participants would advise topical NSAIDs for osteoarthritis and musculoskeletal pain, though be mindful to monitor the renal function and blood pressure. There was a variance in comments in advising use in CKD (eGFR45 mL/min) from avoidance in those with an eGFR30 mL/min to minimal concern. Most respondents (n = 55, 91.7%) had not encountered an acute kidney injury (AKI) suspected from topical NSAID use. Of the five that did, three were thought to be an adverse renovascular event and two were uncertain. All patients had an eGFR45 mL/min, all had recovery f their renal function with NSAID cessation.Patients commonly use topical NSAIDs, often without the physician's knowledge. Most respondents would recommend their use in osteoarthritis and musculoskeletal pain, though with caution in CKD. While an AKI is uncommon due to topical NSAIDs, it may occur, especially in those with CKD. |
| Databáze: | OpenAIRE |
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