Arrhythmias due to Inherited and Acquired Abnormalities of Ventricular Repolarization
Autor: | Maurizio Lunati, Giuseppe Bagliani, Helou Johny, Carlo Pappone, Emanuela T. Locati, Franco Cecchi |
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Přispěvatelé: | Locati, E. T., Bagliani, G., Cecchi, F., Johny, H., Lunati, M., Pappone, C. |
Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
QT interval
Short QT Syndrome medicine.medical_specialty Benign early repolarization Long QT syndrome Torsades de pointes 030204 cardiovascular system & hematology Ventricular tachycardia Sudden death 03 medical and health sciences Electrocardiography 0302 clinical medicine T-wave alternan Physiology (medical) Internal medicine Medicine Humans cardiovascular diseases 030212 general & internal medicine business.industry Short QT syndrome Arrhythmias Cardiac medicine.disease Ventricular repolarization Ventricular fibrillation Ventricular Fibrillation cardiovascular system Cardiology Ventricular arrhythmia Cardiology and Cardiovascular Medicine business Human |
Popis: | Several acquired and congenital disease conditions and many cardiac and noncardiac drugs affect ventricular repolarization and increase susceptibility to ventricular arrhythmias. Abnormal ventricular repolarization can be reflected on the surface ECG by prolonged or shortened QT interval, early repolarization, and abnormal T-wave configuration. Reduced outward K+ currents and abnormal or increased sodium or calcium currents increase the vulnerability to ventricular arrhythmias. Multiple mechanisms give rise to ventricular arrhythmias in conditions of congenital or acquired abnormal ventricular repolarization. Ventricular arrhythmias associated with abnormalities of ventricular repolarization typically are rapid, usually polymorphic, ventricular tachycardia or torsades de pointes, often degenerating into ventricular fibrillation. |
Databáze: | OpenAIRE |
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