Treatment of Soft-Tissue Necrosis of the Pyriform Sinus Using Pentoxyllifylline and Tocopherol
| Autor: | Jamie Tibbo, Aileen Feschuk, Katie Oxford |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty pentoxyllifylline pento business.industry oropharyngeal cancer General Engineering food and beverages tocopherol pentoclo Pyriform Sinus Otolaryngology Oncology medicine Radiation Oncology osteoradionecrosis Soft tissue necrosis head and neck cancer Tocopherol business soft tissue necrosis |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Radiotherapy of the head and neck can often lead to complications and side effects, including osteoradionecrosis and soft tissue necrosis. One relatively well-established method of treating osteoradionecrosis includes the PENTOCLO protocol, which consists of Pentoxyllifylline, Tocopherol, and Clodronate. Despite its success in the treatment of osteoradionecrosis, the effectiveness of components of the PENTOCLO protocol in treating soft tissue necrosis of the head and neck is underexplored. This case study reviews the successful treatment of a pyriform sinus ulcer that developed after the use of radiotherapy in treating a T3N2b squamous cell carcinoma. The treatment plan used Pentoxyllifylline and Tocopherol, and omitted Clodronate, and can therefore be referred to as a PENTO protocol. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|