Advances in platelet function testing—light transmission aggregometry and beyond
| Autor: | Caroline Vayne, François Mullier, Marie Lordkipanidzé, Jessica Le Blanc |
|---|---|
| Přispěvatelé: | Université de Montréal. Faculté de pharmacie, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Laboratoire de biologie clinique |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Platelets
medicine.medical_specialty Light transmission Standardization media_common.quotation_subject lcsh:Medicine Review 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Medicine Medical physics Function (engineering) 030304 developmental biology media_common standardization 0303 health sciences Light transmission aggregometry business.industry lcsh:R Platelet functional tests General Medicine Limiting Clinical Practice Fully automated platelets light transmission aggregometry business platelet functional tests |
| Zdroj: | Journal of clinical medicine, Vol. 9, no. 8, p. E2636 [1-18] (2020) Journal of Clinical Medicine, Vol 9, Iss 2636, p 2636 (2020) Journal of Clinical Medicine |
| Popis: | Platelet function testing is essential for the diagnosis of hemostasis disorders. While there are many methods used to test platelet function for research purposes, standardization is often lacking, limiting their use in clinical practice. Light transmission aggregometry has been the gold standard for over 60 years, with inherent challenges of working with live dynamic cells in specialized laboratories with independent protocols. In recent years, standardization efforts have brought forward fully automated systems that could lead to more widespread use. Additionally, new technical approaches appear promising for the future of specialized hematology laboratories. This review presents developments in platelet function testing for clinical applications. |
| Databáze: | OpenAIRE |
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