Assessment of paraspinal neurogenic tumors with diffusion-weighted MR imaging
| Autor: | Germeen Albair Ashmalla, Ahmed Abdel Khalek Abdel Razek |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Neoplasms Nerve Tissue Sensitivity and Specificity 030218 nuclear medicine & medical imaging Diagnosis Differential Young Adult 03 medical and health sciences 0302 clinical medicine Biopsy Peripheral Nerve Sheath Tumors Retrospective analysis medicine Humans Orthopedics and Sports Medicine Child Diffusion-Weighted MR Imaging Retrospective Studies medicine.diagnostic_test business.industry Significant difference Area under the curve Middle Aged Mr imaging Spine Diffusion Magnetic Resonance Imaging Female Surgery Neurosurgery Nuclear medicine business 030217 neurology & neurosurgery |
| Zdroj: | European Spine Journal. 27:841-846 |
| ISSN: | 1432-0932 0940-6719 |
| DOI: | 10.1007/s00586-017-5265-6 |
| Popis: | To assess paraspinal neurogenic tumors with diffusion-weighted MR imaging. Retrospective analysis was done upon 34 patients with paraspinal neurogenic tumors that underwent diffusion-weighted MR imaging. The ADC values of the mediastinal neurogenic tumors were calculated and correlated with biopsy results. The ADC of benign paraspinal neurogenic tumors (1.5 ± 0.28 × 10−3 mm2/s) was significantly higher (P = 0.001) than that of malignant peripheral nerve sheath tumors (0.995 ± 0.198 × 10−3 mm2/s). Selection of 1.15 × 10−3 mm2/s as a cut-off point for differentiating malignant from benign neurogenic tumors revealed an area under the curve of 0.885, an accuracy of 91.1%, a sensitivity of 90.9%, and specificity of 91.3%. There was significant difference (P = 0.04) in the ADC of schwannomas (1.55 ± 0.29 × 10−3 mm2/s) from neurofibromas (1.33 ± 0.08 × 10−3 mm2/s). The cut-off ADC value of 1.44 × 10−3 mm2/s was used to differentiate schwannomas and neurofibromas with an area under the curve of 0.86, an accuracy of 82.6%, a sensitivity of 100%, and a specificity of 76.5%. Diffusion-weighted MR imaging is imaging parameter that can be used for differentiation of benign from malignant paraspinal neurogenic tumors. |
| Databáze: | OpenAIRE |
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