Modular Polymer-Caged Nanobins as a Theranostic Platform with Enhanced Magnetic Resonance Relaxivity and pH-Responsive Drug Release
| Autor: | Thomas J. Meade, Bong Jin Hong, SonBinh T. Nguyen, Daniel J. Mastarone, Keith W. MacRenaris, Ying Song, Sang Min Lee, Thomas V. O'Halloran |
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| Rok vydání: | 2010 |
| Předmět: |
Materials science
medicine.diagnostic_test Polymers Gadolinium education Contrast Media chemistry.chemical_element Antineoplastic Agents Magnetic resonance imaging General Chemistry General Medicine Deoxycytidine Magnetic Resonance Imaging Gemcitabine Article Catalysis Nuclear magnetic resonance chemistry In vivo Drug delivery Drug release medicine Biomedical engineering |
| Zdroj: | Angewandte Chemie. 122:10156-10160 |
| ISSN: | 0044-8249 |
| DOI: | 10.1002/ange.201004867 |
| Popis: | Magnetic resonance imaging (MRI) can provide detailedhigh-resolution, tomographic information of disease tissue inreal time and in vivo. Hence, it has become a powerfuldiagnostic tool for detecting the stages of primary andrecurrent solid tumors and for the assessment of suitabletreatment regimens. Therefore, MRI is a suitable techniquefor use in conjunction with theranostic platforms for the post-treatment evaluation of solid tumors.MRI studies are often conducted by using paramagneticGd |
| Databáze: | OpenAIRE |
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