Long-term effects of deep brain stimulation for essential tremor with subjective and objective quantification via mailed-in questionnaires
Autor: | Scott E. Cooper, Amy Nowacki, Matthew R. Ginsberg, Milind Deogaonkar, Tatiana H. de Oliveira, Ali R. Rezai, Andre G. Machado |
---|---|
Rok vydání: | 2011 |
Předmět: |
Male
medicine.medical_specialty Deep brain stimulation Activities of daily living medicine.medical_treatment Deep Brain Stimulation Essential Tremor MEDLINE Time Quality of life (healthcare) Patient satisfaction Surveys and Questionnaires Activities of Daily Living Medicine Humans Aged Aged 80 and over Essential tremor business.industry Standard treatment Data Collection Middle Aged medicine.disease Prognosis nervous system diseases Term (time) Patient Satisfaction Physical therapy Quality of Life Surgery Female Neurology (clinical) business Follow-Up Studies |
Zdroj: | Stereotactic and functional neurosurgery. 90(6) |
ISSN: | 1423-0372 |
Popis: | Background: Deep brain stimulation (DBS) is a standard treatment for patients with disabling essential tremor. The short-term efficacy rate is well established. Objectives: To assess the long-term effects of DBS in our series and evaluate the durability of the effects over time. Methods: Eighty-four patients implanted with unilateral or bilateral DBS for essential tremor were asked to complete three mailed-in questionnaires to assess DBS efficacy objectively and subjectively. Results: Twenty-six patients responded, with a median follow-up of 41 months. Approximately half of the patients had more than 48 months of follow-up. At the time of follow-up, the Tremor Rating Scale was reduced from a mean score of 7 (5–8) to 3 (2–3) with DBS OFF and ON, respectively. Quality of life, measured with a subset of items of the ADL Taxonomy, improved from a mean of 26 (23–33) to 12 (12–14), comparing DBS OFF and ON. No significant differences were seen when comparing efficacy at short- (48 months) follow-ups. Conclusion: DBS has long-term efficacy for tremor control. This is associated with sustained benefits in quality of life. The duration of the follow-up was not associated with any significant difference in efficacy. |
Databáze: | OpenAIRE |
Externí odkaz: |