Respiratory Failure in Children With Hemato-oncological Diseases Admitted to the PICU
| Autor: | Montserrat Nieto-Moro, Ana Serrano-González, Juan Casado-Flores, Alberto García-Salido, Beatriz Cabeza-Martín, Ignacio Mastro-Martínez, M.I. Iglesias-Bouzas, Gonzalo Oñoro |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Intensive Care Units Pediatric medicine Humans Respiratory system Child Intensive care medicine Survival rate Retrospective Studies Pediatric intensive care unit Mechanical ventilation business.industry Mortality rate Respiratory infection Retrospective cohort study Hematology Prognosis Respiration Artificial Hospitalization Survival Rate Oncology Respiratory failure Hematologic Neoplasms Pediatrics Perinatology and Child Health Emergency medicine Female Respiratory Insufficiency business Follow-Up Studies |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 37:449-454 |
| ISSN: | 1077-4114 |
| DOI: | 10.1097/mph.0000000000000377 |
| Popis: | Respiratory failure (RF) is a main cause of pediatric intensive care unit (PICU) admission in children with hemato-oncological diseases. We present a retrospective chart review of children admitted to our PICU because of RF (January 2006 to December 2010). The aims of this study are the following: (1) to describe the demographical and clinical characteristics and respiratory management of these children; and (2) to identify the factors associated with mechanical ventilation (MV) and mortality. A total of 69 patients, encompassing 88 episodes, were included (55/88 cases were hypoxemic RF). The first respiratory support at PICU admission was, in decreasing order of frequency, high-flow oxygen nasal cannula (HFNC; 50/88), noninvasive ventilation (NIV; 13/88), and oxygen nasal cannula (16/88). MV was necessary in 47/88 episodes, 38/47 after another respiratory support. In 18/28 children with initial NIV, MV was required later. MV was associated with O-PRISM score, NIV requirement, suspected respiratory infection, and days of PICU treatment. Patients without MV showed an increased survival rate (P=0.001). In summary, the hypoxemic RF was the main cause of PICU admission, and HFNC or NIV was almost always the first respiratory support. The use of MV was associated with a higher mortality rate. The utility of precocious HFNC or NIV should be investigated in larger clinical studies. |
| Databáze: | OpenAIRE |
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