The distinctive sleep pattern of the human calcarine cortex: A stereo-electroencephalographic study
| Autor: | Luigi De Gennaro, Michele Ferrara, Ivana Sartori, Lino Nobili, Fabio Moroni, Maurizio Gorgoni, Simone Sarasso |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
calcarine cortex
EEG power local sleep pattern sleep spindles stereo-EEG Homeostasis Humans Sleep Sleep Stages Sleep REM Electroencephalography Sleep Slow-Wave Posterior parietal cortex Sleep spindle Non-rapid eye movement sleep 03 medical and health sciences Epilepsy 0302 clinical medicine Physiology (medical) Cortex (anatomy) medicine 030304 developmental biology 0303 health sciences medicine.diagnostic_test business.industry Eye movement medicine.disease Sleep in non-human animals medicine.anatomical_structure REM Slow-Wave Neurology (clinical) business Neuroscience 030217 neurology & neurosurgery |
| Popis: | Study Objectives The aim of this study was to describe the spontaneous electroencephalographic (EEG) features of sleep in the human calcarine cortex, comparing them with the well-established pattern of the parietal cortex. Methods We analyzed presurgical intracerebral EEG activity in calcarine and parietal cortices during non-rapid eye movement (NREM) and rapid eye movement (REM) sleep in seven patients with drug-resistant focal epilepsy. The time course of the EEG spectral power and NREM vs REM differences was assessed. Sleep spindles were automatically detected. To assess homeostatic dynamics, we considered the first vs second half of the night ratio in the delta frequency range (0.5–4 Hz) and the rise rate of delta activity during the first sleep cycle. Results While the parietal area showed the classically described NREM and REM sleep hallmarks, the calcarine cortex exhibited a distinctive pattern characterized by: (1) the absence of sleep spindles; (2) a large similarity between EEG power spectra of NREM and REM; and (3) reduced signs of homeostatic dynamics, with a decreased delta ratio between the first and the second half of the night, a reduced rise rate of delta activity during the first NREM sleep cycle, and lack of correlation between these measures. Conclusions Besides describing for the first time the peculiar sleep EEG pattern in the human calcarine cortex, our findings provide evidence that different cortical areas may exhibit specific sleep EEG pattern, supporting the view of sleep as a local process and promoting the idea that the functional role of sleep EEG features should be considered at a regional level. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|