IAPP Mimic Blocks Aβ Cytotoxic Self-Assembly: Cross-Suppression of Amyloid Toxicity of Aβ and IAPP Suggests a Molecular Link between Alzheimer's Disease and Type II Diabetes
Autor: | Aphrodite Kapurniotu, Li-Mei Yan, Marianna Tatarek-Nossol, Erika Andreetto, Aleksandra Velkova |
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Rok vydání: | 2007 |
Předmět: |
Amyloid
Cell Survival Molecular Sequence Data Protein design Disease PC12 Cells Catalysis Type ii diabetes Microscopy Electron Transmission Alzheimer Disease Biomimetic Materials Animals Cytotoxic T cell Amino Acid Sequence Protein Precursors Amyloid beta-Peptides Chemistry P3 peptide General Chemistry Amyloid fibril Islet Amyloid Polypeptide Rats Diabetes Mellitus Type 2 Toxicity Cancer research |
Zdroj: | Angewandte Chemie International Edition. 46:1246-1252 |
ISSN: | 1521-3773 1433-7851 |
Databáze: | OpenAIRE |
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