The effect of different contraceptive methods on the vaginal microbiome
Autor: | Carlo Bastianelli, Paola Bianchi, Manuela Farris, Giuseppe Benagiano |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Female sex hormones
medicine.drug_class combined hormonal contraceptives Physiology intrauterine devices progestin-only contraceptives vaginal microbiome vaginal rings 030226 pharmacology & pharmacy 03 medical and health sciences 0302 clinical medicine Contraceptive Agents Lactobacillus Animals Humans Medicine Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics Lactobacillus species biology business.industry Microbiota Vaginosis Bacterial General Medicine biology.organism_classification medicine.disease Contraception 030220 oncology & carcinogenesis Vagina Vaginal microbiome Female Bacterial vaginosis business Dysbiosis Progestin Hormone |
Popis: | Introduction: Following a historical overview, the effect of different contraceptive methods on vaginal microbiome has been reviewed and summarized.Areas covered: Effects of combined hormonal contraceptives (oral or vaginal) and of progestin only (injectable and implantable), intrauterine devices/systems (copper- or levonorgestrel-releasing), on vaginal microbiome. In addition, mention is made of vaginal rings releasing antiviral drugs and lactic acid.Expert opinion: The vaginal microbiota (VM) is unique in that it is normally dominated by Lactobacillus species providing a degree of protection against infections; this however may vary, depending on the species and strains of Lactobacillus. Bacterial Vaginosis represents the most common dysbiosis of the VM and its prevalence can be influenced by use of contraception. Available evidence indicates that, under the influence of oral or systemically administered female sex hormones, there is apromotion of vaginal eubiosis, with aprevalence of ahealthy VM in which Lactobacilli predominate. |
Databáze: | OpenAIRE |
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