Effects of lead on hepatocyte ultrastructure in Carassius carassius (L.) var. auratus
| Autor: | E. Barbanti, Antonella Franchini, A. M. Bolognani Fantin |
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| Rok vydání: | 1991 |
| Předmět: |
Time Factors
Carassius carassius Golgi Apparatus Biology Endoplasmic Reticulum chemistry.chemical_compound symbols.namesake Lipid droplet Goldfish medicine Animals Glycogen Endoplasmic reticulum Cell Biology General Medicine Anatomy Golgi apparatus Molecular biology Chromatin Mitochondria Microscopy Electron medicine.anatomical_structure chemistry Lead Liver Hepatocyte symbols Cytochemistry Ultrastructure Lysosomes Developmental Biology |
| Zdroj: | Tissuecell. 23(6) |
| ISSN: | 0040-8166 |
| Popis: | Subcellular modifications in hepatocytes of Carassius carassius var. auratus subjected to 24 hr and 48 hr sublethal acute lead (5mg·1 −1 ) exposure were studied by electron microscopy. Cytological alterations were observed after 24 hr of treatment and became more evident after 48 hr. Lead induced an increase in nuclear heterochromatin and alterations in mitochondria, endoplasmic reticulum and Golgi complex ultrastructure. Glycogen granula decreased, and secondary lysosomes and lipid droplets increased. Furthermore, intracytoplasmic lumina with microvilli-bearing surfaces and numerous autophagic vacuola were observed after 48 hr of exposure. |
| Databáze: | OpenAIRE |
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