Efficacy of Unsupervised Self-Collected Mid-Turbinate FLOQSwabs for the Diagnosis of Coronavirus Disease 2019 (COVID-19)

Autor: Carmen Cocca, Giovambattista Capasso, Luca Rinaldi, Marco Pizza, Fabio Pizza, Felice Di Perna, Santina Castriciano, Anna Bellizzi, Egildo Luca D'Andrea, Alessia Maria Cossu, Alessandra Fucci, Pasquale Iuliano, Vincenzo Messina, Nicola Coppola, Chiara Pelosi, Marianna Scrima, Angelo Frieri, Fabio Lo Calzo, Paolo Maggi, Michele Caraglia
Přispěvatelé: D'Andrea, Egildo Luca, Cossu, Alessia Maria, Scrima, Marianna, Messina, Vincenzo, Iuliano, Pasquale, Di Perna, Felice, Pizza, Marco, Pizza, Fabio, Coppola, Nicola, Rinaldi, Luca, Bellizzi, Anna Maria, Pelosi, Chiara, Cocca, Carmen, Frieri, Angelo, Lo Calzo, Fabio, Capasso, Giovambattista, Castriciano, Santina, Maggi, Paolo, Fucci, Alessandra, Caraglia, Michele
Rok vydání: 2021
Předmět:
Zdroj: Viruses, Vol 13, Iss 1663, p 1663 (2021)
Viruses
Volume 13
Issue 8
ISSN: 1999-4915
DOI: 10.3390/v13081663
Popis: Context: The Global Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic has resulted in explosive patterns of transmission in most countries. Nasopharyngeal swabs were the specimen’s collection tools recommended for the diagnosis of SARS-CoV-2 infection, and for monitoring infection outbreaks in communities. Our objective was to report the quality and efficacy of unsupervised self-collected mid turbinate “dry FLOQSwabs” (MT FLOQSwabs) (56380CS01, Copan). There were 111 specimens collected for the study: 36 by health care personnel, from themselves, to verify the quality and efficacy of mid-turbinate swabs
75 to compare and assess the diagnostic performance, among health care personnel, of nasopharyngeal swabs and self-collected mid-turbinate FLOQSwabs. A collection of 51 specimens was enrolled to define the efficacy of the Testami program (validation). Our analyses demonstrate that self-collected mid-turbinate dry swabs ensure an accuracy of 97.3%, as compared to the standard nasopharyngeal swabs collected by health care workers. Furthermore, the mid-turbinate FLOQSwabs can be stored without medium for six days at room temperature without affecting the molecular diagnosis of the SARS-CoV-2 virus infection. Self-collection of diagnostic specimens at home could offer an avenue to increase testing availability for SARS-CoV-2 infection without asking people to travel to a clinic or a laboratory, thus reducing people’s exposure to infection. Our findings demonstrate that unsupervised self-collection swabs, transported dry, are sensitive, practical and easy-to-use tools and should be considered for diagnosis of SARS-COV-2 and coronavirus disease 2019 (COVID-19) surveillance.
Databáze: OpenAIRE
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