Wet-priming extracorporeal membrane oxygenation device maintains sterility for up to 35 days of follow-up
| Autor: | Alessandro Gandaglia, Gino Gerosa, Roberta Danesin, Fabio Zanella, Filippo Naso, P Balboni, Michele Spina |
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| Rok vydání: | 2012 |
| Předmět: |
Advanced and Specialized Nursing
medicine.medical_specialty Time Factors Sterility business.industry medicine.medical_treatment Priming (immunology) Membranes Artificial General Medicine Surgery Extracorporeal Membrane Oxygenation surgical procedures operative Extracorporeal membrane oxygenation medicine Surgical equipment Radiology Nuclear Medicine and imaging In patient Cardiology and Cardiovascular Medicine business Safety Research Oxygenator |
| Zdroj: | Perfusion. 28:208-213 |
| ISSN: | 1477-111X 0267-6591 |
| Popis: | In emergency cases, rapid extracorporeal membrane oxygenation (ECMO) device initialization is able to drastically reduce the incidence of patient morbidity and/or mortality. Pre-assembled and ready-to-use ECMO circuits might save up to 30-60 critical minutes in patient management. Six ECMO circuits (Oxygenator D905 EOS with REVOLUTION™ pump and Sorin PTS) were assembled in the operating room in standard conditions and then placed at 37°C for 35 days in order to evaluate possible contamination and ingrowth of micro-organisms. Every 7 days after ECMO circuit assembly and wet-priming, samples of priming fluid were analyzed to verify the presence/absence of possible common contaminants ( Enterobacteriaceae, Staphylococcus aureus and fungi). Moreover, two supplementary circuits, used as positive controls, were deliberately inoculated with a known concentration of a Escherichia coli strain and prime samplings carried out at different time-points to determine bacterial growth rate. Sterility was maintained in the ECMO circuits for up to 35 days. |
| Databáze: | OpenAIRE |
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