Salmonella-induced immune response reduces recurrence and tumor dissemination in preclinical melanoma model

Autor: Amy Mónaco, María C. Plata, Sofía Chilibroste, Magdalena Vola, Jose A. Chabalgoity, María Moreno
Rok vydání: 2021
Předmět:
Zdroj: Current research in immunology. 3
ISSN: 2590-2555
Popis: Localized melanoma is easy to remove by surgery, resulting in a high five-year relative survival rate. However, when disseminated the disease management is challenging. The use of immunotherapies, such as anti-checkpoint monoclonal antibodies, has improved treatment options but still only a small percentage of patients responds to these expensive treatments. In this work, we apply a bacteria-based immunotherapy using LVR01, an attenuated
Databáze: OpenAIRE