Prevalence of autism and attention-deficit-hyperactivity disorder in Down syndrome: a population-based study
| Autor: | Elisabeth Fernell, Anne Isaksson, Cathrine Göransson, Marie Åberg, Bodil Ekstam, Jan Gustafsson, Agneta Holmbom, Ulrika Wester Oxelgren, Åsa Myrelid, Göran Annerén |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Down syndrome medicine.medical_specialty Neurology Adolescent Population behavioral disciplines and activities Community Health Planning Cohort Studies 03 medical and health sciences 0302 clinical medicine Developmental Neuroscience 030225 pediatrics mental disorders medicine Prevalence Attention deficit hyperactivity disorder Humans Autistic Disorder education Psychiatry Child Neurologic Examination Psychiatric Status Rating Scales education.field_of_study medicine.disease Population based study Autism spectrum disorder Attention Deficit Disorder with Hyperactivity Child Preschool Pediatrics Perinatology and Child Health Autism Female Neurology (clinical) Down Syndrome Psychology 030217 neurology & neurosurgery Cohort study |
| Zdroj: | Developmental medicine and child neurology. 59(3) |
| ISSN: | 1469-8749 |
| Popis: | To investigate the prevalence of autism spectrum disorder (ASD) and attention-deficit-hyperactivity disorder (ADHD) in a population-based group of children and adolescents with Down syndrome, and to relate the findings to level of intellectual disability and to medical conditions.From a population-based cohort of 60 children and adolescents with Down syndrome, 41 individuals (29 males, 12 females; mean age 11y, age range 5-17y) for whom parents gave consent for participation were clinically assessed with regard to ASD and ADHD. The main instruments used were the Autism Diagnostic Interview-Revised, Autism Diagnostic Observation Schedule, Swanson, Nolan, and Pelham-IV Rating Scale, and the Adaptive Behavior Assessment System-II.High rates of ASD and ADHD were found: 17 (42%) and 14 (34%) of the 41 children met DSM criteria for ASD and ADHD respectively.Children with Down syndrome and coexisting neurodevelopmental/neuropsychiatric disorders in addition to intellectual disability and medical disorders constitute a severely disabled group. Based on the results, we suggest that screening is implemented for both ASD and ADHD, at the age of 3 to 5 years and early school years respectively, to make adequate interventions possible. |
| Databáze: | OpenAIRE |
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