Terbium Radionuclides for Theranostics Applications: A Focus On MEDICIS-PROMED

Autor: T. Sounalet, Thierry Stora, I. Zahi, R. Formento Cavaier, Ferid Haddad
Přispěvatelé: Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Advanced Accelerator Applications, ARRONAX - (GIP) Groupement d'Intérêt Public [Saint-Herblain] (Institut de Recherche Public), European Organization for Nuclear Research (CERN), Université de Nantes - Faculté des Sciences et des Techniques, Cyclotron ARRONAX
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Physics Procedia
Physics Procedia, Elsevier, 2017, 90, pp.157-163. ⟨10.1016/j.phpro.2017.09.053⟩
ISSN: 1875-3892
DOI: 10.1016/j.phpro.2017.09.053⟩
Popis: A new facility, named CERN-MEDICIS, is under construction at CERN to produce radionuclides for medical applications. In parallel, the MEDICIS-PROMED, a Marie Sklodowska-Curie innovative training network of the Horizon 2020 European Commission‘s program, is being coordinated by CERN to train young scientists on the production and use of innovative radionuclides and develop a network of experts within Europe. One program within MEDICIS-PROMED is to determine the feasibility of producing innovative radioisotopes for theranostics using a commercial middle-sized high-current cyclotron and the mass separation technology developed at CERN-MEDICIS. This will allow the production of high specific activity radioisotopes not achievable with the common post-processing by chemical separation. Radioisotopes of scandium, copper, arsenic and terbium have been identified. Preliminary studies of activation yield and irradiation parameters optimization for the production of Tb-149 will be described.
Databáze: OpenAIRE