A Multicenter Comparison of 2 Point-of-Care Activated Clotting Time Test Systems
| Autor: | Tim Hesselink, Georgios J. Vlachojannis, Antoinette Milané-Santman, Johannes G. Krabbe, Marcoen F. Scholten, Evelien W.M. Kemna, Mark W.M. Schellings, Florian Falter |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Whole Blood Coagulation Time medicine.diagnostic_test business.industry Point-of-Care Systems Activated clotting time Reproducibility of Results General Medicine Gold standard (test) Sensitivity and Specificity Point-of-Care Testing medicine Humans Intensive care medicine business Point of care |
| Zdroj: | The Journal of Applied Laboratory Medicine. 4:468-470 |
| ISSN: | 2475-7241 |
| Popis: | To the Editor: Activated clotting time (ACT) is used to monitor unfractionated heparin anticoagulation during invasive procedures such as percutaneous coronary or electrophysiology interventions. There are several point-of-care (POC) methods available for ACT measurement and results can vary substantially (1–3), making thresholds method dependent. Values published in guidelines are mostly empiric or based on small-scale studies with different POC devices (4). It is important to realize that there is no “gold standard” ACT method and therefore no “true” ACT. These limitations demonstrate the significance of comparing different POC devices over a wide analytical range, to define optimal therapeutic thresholds for specific devices. We report the comparison between Hemochron Signature Elite (ITC) and the i-STAT (Abbott) … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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