Effect of Gender on Results of Percutaneous Edge-to-Edge Mitral Valve Repair With MitraClip System
| Autor: | Per Jacobsen, Neil Moat, Nikolaj Ihlemann, Olaf Franzen, Rodrigo Estévez-Loureiro, Susanna Price, Gary Cheung, Lars Søndergaard, Carlo Di Mario, Michele Pighi, Gianni Dall'Ara, Matteo Ghione, Magnus Settergren, Tine Streit Rosenberg, Reidar Winter |
|---|---|
| Přispěvatelé: | Estévez-Loureiro, Rodrigo, Settergren, Magnu, Winter, Reidar, Jacobsen, Per, Dall'ara, Gianni, Sondergaard, Lar, Cheung, Gary, Pighi, Michele, Ghione, Matteo, Ihlemann, Nikolaj, Moat, Neil E., Price, Susanna, Streit Rosenberg, Tine, Di Mario, Carlo, Franzen, Olaf |
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Percutaneous Denmark medicine.medical_treatment Sex Factor Kaplan-Meier Estimate Prosthesis Design Follow-Up Studie Postoperative Complications Sex Factors Retrospective Studie Internal medicine medicine Humans Myocardial infarction Survival rate Aged Retrospective Studies Sweden Mitral regurgitation Mitral valve repair business.industry Incidence MitraClip Mitral Valve Insufficiency Retrospective cohort study medicine.disease United Kingdom Surgery Survival Rate Heart Valve Prosthesi Treatment Outcome Female Follow-Up Studies Heart Valve Prosthesis Cohort Cardiology Postoperative Complication Cardiology and Cardiovascular Medicine business Human |
| Zdroj: | The American Journal of Cardiology. 116:275-279 |
| ISSN: | 0002-9149 |
| Popis: | Knowledge regarding gender-specific results of percutaneous edge-to-edge mitral valve repair is scarce. The aim of this study was to investigate gender differences in outcomes in a cohort of patients treated with MitraClip implantation. A multicenter registry of 173 patients treated with MitraClip prostheses from 2009 to 2012 at 3 experienced centers was performed. One hundred nine patients (63%) were men. Men were younger (mean age 73 ± 10 vs 79 ± 9 years, p = 0.001) and had a higher prevalence of previous coronary bypass graft surgery (34% vs 13%, p = 0.002), previous myocardial infarction (46% vs 20%, p = 0.001), and diabetes mellitus (26% vs 11%, p = 0.020). There were no differences regarding New York Heart Association (NYHA) functional class before the intervention (NYHA class III or IV in 95% of men vs 97% of women, p = 0.472) or the cause of mitral regurgitation (MR) (functional in 58% of men vs 48% of women, p = 0.233). Men exhibited significantly larger ventricles (mean indexed left ventricular end-systolic diameter 2.4 ± 0.8 vs 2.0 ± 1.6 cm/m2, p = 0.002, and mean indexed left ventricular end-diastolic volume 92.7 ± 46.1 vs 59.9 ± 24.6 ml/m2, p |
| Databáze: | OpenAIRE |
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