Endocrinopathies in thalassemia - a review

Autor:	Shapur Ikhtaire, Tahniyah Haq, Farzana Rahman, Nishat Nayla Aurpa
Rok vydání:	2021
Předmět:	Pediatrics medicine.medical_specialty business.industry hemic and lymphatic diseases Thalassemia medicine Medicine business medicine.disease
Zdroj:	IMC Journal of Medical Science, Vol 15, Iss 1, Pp 1-9 (2021)
ISSN:	2519-1586 2519-1721
DOI:	10.3329/imcjms.v15i1.54202
Popis:	Improved treatment has increased survival of patients with thalassemia. However, they still suffer from several endocrine complications mainly as a result of iron overload from multiple transfusions. Endocrinopathies manifest as early as the first decade of life, affecting growth, puberty, psychological development and quality of life. The presence of concomitant anemia, chronic liver disease and cardiomyopathy affect the development and treatment of endocrine disorders, making endocrinopathies in thalassemia a complex disorder. This review focuses on the pathogenesis, diagnosis and treatment of endocrinopathies in transfusion and non transfusion dependent thalassemia. The main points that should be considered in the management of endocrine disorders in a patient with thalassemia are highlighted in this review. IMC J Med Sci 2021; 15(1): 008. OPEN ACCESS *Correspondence: Tahniyah Haq, Department of Endocrinology, Room 1620, 15th Floor, Block D, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka 1000, Bangladesh. Email: tahniyah81@gmail.com
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563491080f4af895865b5a48a6261a52 https://doi.org/10.3329/imcjms.v15i1.54202 Zobrazit plný text záznamu