THE INFLUENCE OF ADRENERGIC NERVES ON THE RESPONSE OF BLOOD VESSELS IN THE RABBIT EAR TO 2-PHENYLALANINE-8-LYSINE VASOPRESSIN (OCTAPRESSIN)
| Autor: | DC Gerke, DB Frewin, BR Frost |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Octapressin
medicine.medical_specialty Reserpine Vascular smooth muscle Vasopressins Clinical Biochemistry Immunology Phenylalanine In Vitro Techniques Veins Adrenergic Nerves Phentolamine Cocaine Internal medicine otorhinolaryngologic diseases medicine Animals Ear External Sympathectomy Felypressin Lysine vasopressin Denervation business.industry Sodium Muscle Smooth Long-term potentiation Arteries Cell Biology General Medicine Propranolol Endocrinology Nialamide Rabbits Adrenergic Fibers business medicine.drug |
| Zdroj: | Australian Journal of Experimental Biology and Medical Science. 54:467-474 |
| ISSN: | 0004-945X |
| DOI: | 10.1038/icb.1976.47 |
| Popis: | The blood vessels in the rabbit ear have been used to investigate the effects of octapressin on vascular smooth muscle. Continuous administration of this drug resulted in tachphlatis. Cocaine enhanced the response of the ear to octapressin; however, this potentiation was not evident when phentolamine was concurrently added to the perfusate. Denervation and reserpinisation of the ear also eliminated the potentiation of octapressin's response by cocaine. The results suggest that there is a small, indirect sympathomimetic component involved in octapressin's action on the vasculature. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text