Analgesic effect of non-nutritive sucking in term neonates: A randomized controlled trial
| Autor: | Le Duc Don, Ong Phuc Thinh, Nguyen Lam Vuong, Nguyen Vo Tan Danh, Hai Vu-Ngoc, Nguyen Tien Huy, Nguyen Cao Minh Uyen, Vu Thi Tuong Vi, Nguyen Tran Thanh Truc, Pham Diep Thuy Duong |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Analgesic effect
Male medicine.medical_specialty Heel Sedation scale law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Pain assessment law 030225 pediatrics Internal medicine Medicine Humans Pain Management 030212 general & internal medicine Adverse effect Pain Measurement business.industry Infant Newborn lcsh:RJ1-570 lcsh:Pediatrics Term neonates Pacifiers medicine.anatomical_structure Sucking Behavior Pediatrics Perinatology and Child Health Pacifier Female business |
| Zdroj: | Pediatrics and Neonatology, Vol 61, Iss 1, Pp 106-113 (2020) |
| ISSN: | 1875-9572 |
| Popis: | Background: Newborns commonly experience pain due to a variety of reasons. Non-nutritive sucking (NNS) is thought to be an effective non-pharmacological method of pain-relief. However, the significant heterogeneity in some systematic reviews limited the certainty of the findings about NNS. Hence, this study was aimed at evaluating the analgesic effect and safety of NNS in healthy term neonates during the heel prick test, using the Neonatal Pain Agitation and Sedation Scale (N-PASS). Methods: In this randomized controlled trial, 42 term infants were included: 22 infants in the intervention group (receiving NNS) and 20 infants in the control group (not receiving NNS). In the intervention group, neonates were given a silicone pacifier 120 s before, during, and 120 s after the heel puncture, while neonates in the control group received routine care. Pain-related outcomes were assessed using the N-PASS at 30s, 60s, 90s, and 120s after the heel prick. Any adverse events during the procedure were noted. The Spearman correlation coefficients between the pain scores on the N-PASS and two other scales (NFCS and NIPS) were calculated at all four moments of evaluation. Results: The mean N-PASS pain scores at 30s, 60s, 90s, and 120s after heel prick were significantly lower in the NNS group than in the control group: 4.73 ± 2.78 vs. 7.90 ± 1.52 (p = 0.0002); 3.64 ± 3.06 vs. 5.55 ± 2.95 (p = 0.052); 2.59 ± 3.08 vs. 5.25 ± 3.51 (p = 0.011); and 2.05 ± 2.94 vs. 4.90 ± 3.99 (p = 0.013), respectively. No adverse events were detected in either group. Our findings revealed a strong positive correlation between the pain scores on the N-PASS and two other scales (NFCS and NIPS), which was statistically significant (p |
| Databáze: | OpenAIRE |
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