Micrometastasis: Neglected enough!
| Autor: | Manjunath Venkatappa, Prathyusha Chavva, Devaraju Devaiah, Vijeev Vasudevan |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
Oncology medicine.medical_specialty Prognostic factor lcsh:R895-920 Sentinel lymph node Metastasis sentinel lymph node Internal medicine medicine Radiology Nuclear Medicine and imaging Molecular detection General Dentistry business.industry Micrometastasis Cancer tumor staging medicine.disease Primary tumor Tumor recurrence lcsh:RK1-715 Otorhinolaryngology lcsh:Dentistry oral field cancerization Lymph business |
| Zdroj: | Journal of Indian Academy of Oral Medicine and Radiology, Vol 29, Iss 2, Pp 111-114 (2017) |
| ISSN: | 0972-1363 |
| DOI: | 10.4103/jiaomr.jiaomr_53_16 |
| Popis: | Oral cancer, being the sixth most common cancer in the world, accounts for approximately 13% of deaths worldwide. Metastasis to the lymph nodes is one of the major prognostic factor for oral cancer. Micrometastasis are microscopic deposits of malignant cells lodged in lymph nodes. Tumor recurrence usually reflects the presence of such deposits which cannot be detected initially by conventional methods. Early screening of such cells using immunological and molecular markers would help in better staging of the primary tumor followed by prompt treatment, thus reducing tumor relapse. Therefore, the concept of micrometastasis has resulted in a paradigm shift in the staging of epithelial tumors and the overall understanding of the malignant process. |
| Databáze: | OpenAIRE |
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