Outcome of children and adolescents with central nervous system tumors in phase I trials

Autor:	Lynley V. Marshall, Luca Bergamaschi, Raquel Hladun-Alvaro, Irene Jiménez, Francisco Bautista, Madhumita Dandapani, Gilles Vassal, Darren Hargrave, Michela Casanova, Fernando Carceller, Andrew D.J. Pearson, Lucas Moreno, Isabelle Aerts, Bruce Morland, Birgit Geoerger, Cécile Giraud, Didier Frappaz, François Doz
Rok vydání:	2017
Předmět:	Male 0301 basic medicine Cancer Research medicine.medical_specialty Neurology Multivariate analysis Adolescent Brain tumor Kaplan-Meier Estimate Central Nervous System Neoplasms 03 medical and health sciences 0302 clinical medicine Internal medicine Outcome Assessment Health Care medicine Humans Child Cause of death Univariate analysis Clinical Trials Phase I as Topic Performance status business.industry Infant Cancer medicine.disease Treatment Outcome 030104 developmental biology Oncology Child Preschool 030220 oncology & carcinogenesis Disease Progression Female Neurology (clinical) business Progressive disease
Zdroj:	Journal of Neuro-Oncology. 137:83-92
ISSN:	1573-7373 0167-594X
DOI:	10.1007/s11060-017-2698-z
Popis:	Central nervous system (CNS) tumors are a leading cause of death in pediatric oncology. New drugs are desperately needed to improve survival. We evaluated the outcome of children and adolescents with CNS tumors participating in phase I trials within the Innovative Therapies for Children with Cancer (ITCC) consortium. Patients with solid tumors aged
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5613b26bf87fef89bba2fd8c29ee0aa8 https://doi.org/10.1007/s11060-017-2698-z Zobrazit plný text záznamu Full text from SpringerLink