Failure of High Pco2in the Duodenal Bulb to Inhibit Gastric Acid Secretion

Autor: Simon J. Rune, Göran Nilsson
Rok vydání: 1971
Předmět:
Zdroj: Acta Physiologica Scandinavica. 81:349-354
ISSN: 1365-201X
0001-6772
DOI: 10.1111/j.1748-1716.1971.tb04909.x
Popis: Gastric acid secretion was stimulated by intravenous infusion of pentagastrin (ICI 50 123) in dogs with Pavlov pouches and isolated pouches of the duodenal bulb. Elevation of the Pco2 to 150 or 700 mm Hg in the bulbar pouches did not reduce the gastric acid output. It is suggested that the high CO2 tension which normally exists in the canine duodenum during periods of stimulated gastric acid secretion is not involved in the activation of the bulbar mechanism inhibiting the gastric acid secretion.
Databáze: OpenAIRE