Failure of High Pco2in the Duodenal Bulb to Inhibit Gastric Acid Secretion
Autor: | Simon J. Rune, Göran Nilsson |
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Rok vydání: | 1971 |
Předmět: |
medicine.medical_specialty
Duodenum Physiology Partial Pressure Hydrochloric acid Biology pCO2 chemistry.chemical_compound Dogs stomatognathic system Internal medicine Duodenal bulb medicine Gastric mucosa Animals Secretion Gastric Juice digestive oral and skin physiology Carbon Dioxide Stimulation Chemical Pentagastrin Endocrinology medicine.anatomical_structure chemistry Gastric Mucosa Injections Intravenous Gastric acid Hydrochloric Acid Peptides medicine.drug |
Zdroj: | Acta Physiologica Scandinavica. 81:349-354 |
ISSN: | 1365-201X 0001-6772 |
DOI: | 10.1111/j.1748-1716.1971.tb04909.x |
Popis: | Gastric acid secretion was stimulated by intravenous infusion of pentagastrin (ICI 50 123) in dogs with Pavlov pouches and isolated pouches of the duodenal bulb. Elevation of the Pco2 to 150 or 700 mm Hg in the bulbar pouches did not reduce the gastric acid output. It is suggested that the high CO2 tension which normally exists in the canine duodenum during periods of stimulated gastric acid secretion is not involved in the activation of the bulbar mechanism inhibiting the gastric acid secretion. |
Databáze: | OpenAIRE |
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