Validation of the Drug Abuse Screening Test (Dast-10): A Study on Illicit Drug Use among Chinese Pregnant Women
| Autor: | Lap Po Lam, Mei Fung Chan, Wing Cheong Leung, Kam Ming Chow, Chun Bong Chow, Judy Wai Ying Ng, Ying Hoo Lam, Chu Sing, Robert Kien Howe Chin, Patrick Ip, Wing Lai Tony Mak |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Drug
Adult medicine.medical_specialty China Urinalysis Screening test Substance-Related Disorders media_common.quotation_subject education Urine Sensitivity and Specificity Article Chinese version Pregnancy medicine Illicit drug Humans Psychiatry media_common Multidisciplinary medicine.diagnostic_test Obstetrics business.industry Illicit Drugs Reproducibility of Results medicine.disease Substance abuse Substance Abuse Detection ROC Curve Female business |
| Zdroj: | Scientific Reports |
| Popis: | We assessed the Chinese version of the Drug Abuse Screening Test (DAST-10) for identifying illicit drug use during pregnancy among Chinese population. Chinese pregnant women attending their first antenatal visit or their first unbooked visit to the maternity ward were recruited during a 4-month study period in 2011. The participants completed self-administered questionnaires on demographic information, a single question on illicit drug use during pregnancy and the DAST-10. Urine samples screened positive by the urine Point-of-Care Test were confirmed by gas chromatography-mass spectrometry. DAST-10 performance was compared with three different gold standards: urinalysis, self-reported drug use and evidence of drug use by urinalysis or self-report. 1214 Chinese pregnant women participated in the study and 1085 complete DAST-10 forms were collected. Women who had used illicit drugs had significantly different DAST-10 scores than those who had not. The sensitivity of DAST-10 for identify illicit drug use in pregnant women ranged from 79.2% to 33.3% and specificity ranged from 67.7% to 99.7% using cut-off scores from ≥1 to ≥3. The ~80% sensitivity of DAST-10 using a cut-off score of ≥1 should be sufficient for screening of illicit drug use in Chinese pregnant women, but validation tests for drug use are needed. |
| Databáze: | OpenAIRE |
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