Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33

Autor:	Adina Zeidler, Jin-Xiong She, Mark C. K. Yang, Jean Francois Bach, James J. Yang, Sarah Eckenrode, Diane Hopkins, Michele P. Marron, Yongsoo Park, Henri Jean Garchon, Chaim O. Jacob, Leslie J. Raffel, Jerome I. Rotter, Manuel Serrano-Ríos, María Teresa Martínez Larrad
Rok vydání:	2000
Předmět:	Genetic Markers Yeast artificial chromosome Candidate gene Immunoconjugates Genetic Linkage Endocrinology Diabetes and Metabolism DNA Recombinant chemical and pharmacologic phenomena Locus (genetics) Biology Abatacept Trinucleotide Repeats Gene mapping Antigens CD Genetic linkage Internal Medicine Humans CTLA-4 Antigen Genetic Predisposition to Disease Cloning Molecular Chromosomes Artificial Yeast Sequence Tagged Sites Genetics Bacterial artificial chromosome Gene map Chromosome Mapping Chromosomes Bacterial Antigens Differentiation Molecular biology Diabetes Mellitus Type 1 Haplotypes Genetic marker Chromosomes Human Pair 2
Zdroj:	Diabetes. 49:492-499
ISSN:	1939-327X 0012-1797
Popis:	Polymorphic markers within the CTLA4 gene on chromosome 2q33 have been shown to be associated with type 1 diabetes. Therefore, a gene responsible for the disease (IDDM12) most likely lies within a region of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5606ed02d3dfb265600cf9c871c53c71 https://doi.org/10.2337/diabetes.49.3.492 Zobrazit plný text záznamu