Two-year clinical outcomes associated with robotic-assisted subthalamic lead implantation in patients with Parkinson’s disease
| Autor: | Nicolas Phielipp, Michelle Paff, Alice S Wang, Sumeet Vadera, Anna Morenkova, Neal Hermanowicz, Frank P.K. Hsu |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Levodopa Time Factors Movement disorders Parkinson's disease Deep brain stimulation Deep Brain Stimulation medicine.medical_treatment Operative Time 030232 urology & nephrology Health Informatics Neurosurgical Procedures Prosthesis Implantation Stereotaxic Techniques 03 medical and health sciences Postoperative Complications 0302 clinical medicine Robotic Surgical Procedures Subthalamic Nucleus Rating scale medicine Humans Lead (electronics) Aged Retrospective Studies business.industry Parkinson Disease Middle Aged medicine.disease Electrodes Implanted Subthalamic nucleus Treatment Outcome 030220 oncology & carcinogenesis Anesthesia Female Surgery medicine.symptom Complication business Follow-Up Studies medicine.drug |
| Zdroj: | Journal of Robotic Surgery. 14:559-565 |
| ISSN: | 1863-2491 1863-2483 |
| DOI: | 10.1007/s11701-019-01025-x |
| Popis: | Few centers have routinely implemented robotic stereotactic systems for deep brain stimulator (DBS) placement. The present study compares clinical outcomes associated with robotic-assisted subthalamic nucleus (STN)-targeted DBS surgery in patients with Parkinson's disease (PD) to those of the traditional frame-based method. A retrospective chart review was performed (February 2013-June 2017). Thirty-three patients were implanted using the Cosman-Roberts-Wells (CRW) frame and 27 patients were implanted using the ROSA robot. Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) or UPDRS part III motor scores and levodopa equivalent daily doses (LEDD) were examined preoperatively and at 6, 12, and 24 months of follow-up. Operative times and complication rates were recorded. For the frame-based group, the reduction in the mean MDS-UPDRS part III motor score compared to baseline was 27% both at 6 and 12 months, and 36.7% at 24 months. For the robotic-assisted group, the reduction in the mean motor score from baseline was 17.6% at 6 months, 19% at 12 months and 21.4% at 24 months. The mean LEDD for the frame-based group decreased by 48.7% at 6 months, 56.7% at 12 months, and 29.7% at 24 months. For the robotic-assisted group, the mean LEDD decreased by 42% at 6 months, 45% at 12 months and 50% at 24 months. There were no significant differences in the mean motor scores and the LEDD reduction between the two groups. Operative times tended to be longer for robotic-assisted DBS surgery. Clinical outcomes associated with robotic-assisted surgery are comparable to those with frame-based surgery. |
| Databáze: | OpenAIRE |
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