The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: an analysis of 618 individuals
| Autor: | Nye-Jan Cheng, Yu-Shien Ko, Shu-Mei Wang, Ying-Shiung Lee, Chi-Tai Kuo, Tsu-Shiu Hsu, Yu-Hsien Ko, Wei-Jan Chen, Shy-Meeng Wu, Chen-Wen Chiang, Chi-Jen Chang |
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| Rok vydání: | 1996 |
| Předmět: |
Genetics
China Heterozygote biology Factor V Population genetics Thrombophlebitis medicine.disease Venous thrombosis Gene Frequency Case-Control Studies Mutation (genetic algorithm) medicine biology.protein Factor V Leiden Humans Point Mutation Allele Allele frequency Gene Alleles Genetics (clinical) Protein C |
| Zdroj: | Human Genetics. 98:176-177 |
| ISSN: | 1432-1203 0340-6717 |
| Popis: | To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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