Full blood count and white cell differential count reference ranges obtained from a healthy urban South African population residing in the Western Cape of South Africa

Autor:	Glenda M. Davison, Francois Smit, Saarah F G Davids, Tandi E. Matsha, Rajiv T Erasmus, Mariza Hoffmann
Rok vydání:	2019
Předmět:	Adult Male Percentile Adolescent Clinical Biochemistry Population Blood count Ethnic group Black People 030204 cardiovascular system & hematology White People 03 medical and health sciences Leukocyte Count South Africa Young Adult 0302 clinical medicine Reference Values Medicine Humans Lymphocytes education education.field_of_study business.industry RED-CELL INDICES Platelet Count Biochemistry (medical) Hematology General Medicine Middle Aged Reference intervals Blood Cell Count Eosinophils African population Western cape Erythrocyte Count Female business 030215 immunology Demography
Zdroj:	International journal of laboratory hematologyREFERENCES. 41(5)
ISSN:	1751-553X
Popis:	BACKGROUND Research has suggested that individuals of African descent have lower white cell and neutrophil counts than Caucasians. These differences could lead to incorrect clinical decisions, and therefore, ethnic-specific reference ranges are required. The Western Cape region of South Africa is uniquely diverse, comprising Caucasian, Mixed Ancestry and those of African descent. The aim of this study was to compare the full blood count and differential counts across the three major ethnic groups residing in this area and to propose appropriate RIs. METHODS The study formed part of the international project led by the Committee on Reference Intervals and Decision Limits (C-RIDL), and therefore, the strict guidelines laid out by the committee were followed. Full blood count and differential counts were performed on a Beckman Coulter ACT 5 diff AL analyser within 2-4 hours of collection and were reported as mean (standard deviation), 2.5th and 97.5th percentiles. Comparisons were analysed using Spss v25 and Statistica v13, and a P value of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f51fa41705ba8ed5a91959f830bb4b https://pubmed.ncbi.nlm.nih.gov/33340394 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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