A patient's perspective on the side effects of tyrosine kinase inhibitors in the treatment of advanced and metastatic gastrointestinal stromal tumors
| Autor: | Deborah van de Wal, Shreenila Venkatesan, Charlotte Benson, Winette TA van der Graaf, Colin D Johnson, Olga Husson, Samantha C Sodergren |
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| Přispěvatelé: | Medical Oncology, Surgery |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Future Oncology, 19(4), 299-314. Future Medicine Ltd. |
| ISSN: | 1744-8301 1479-6694 |
| Popis: | Aim: to provide the gastrointestinal stromal tumor patient's perspective on side effects of tyrosine kinase inhibitors and compare this with that of healthcare professionals. Materials & methods: semi-structured interviews were conducted with 19 patients with an advanced or metastatic gastrointestinal stromal tumor, as well as six healthcare professionals, and five patients paricipated in a focus group. Thematic analysis was used to interpret the data. Results: most participants (n = 29) reported gastrointestinal symptoms followed by tiredness (n = 25), edema (n = 22), muscle cramps (n = 21), skin problems (n = 21), eye problems (n = 11) and trouble sleeping (n = 10). Patients, but not healthcare professionals, reported cognitive problems or symptoms of depression. Conclusion: these results underline the importance of including the patient's perspective, as there is a gap in symptom reporting between patients and healthcare professionals. |
| Databáze: | OpenAIRE |
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