Impact of Rhinitis on Asthma Control in Children: Association With FeNO
| Autor: | Nicolas Molinari, Muriel Varrin, Isabelle Vachier, Ghamartaj Khanbabaee, Philippe Godard, Pascal Chanez, Raphaël Chiron |
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| Přispěvatelé: | Centre Hospitalier Universitaire de Montpellier (CHU Montpellier ), Mathématiques, Informatique et STatistique pour l'Environnement et l'Agronomie (MISTEA), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Lab Biostat, Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Adolescent atopy Statistics Nonparametric Atopy 03 medical and health sciences rhinitis score 0302 clinical medicine nitric oxide Internal medicine Asthma control medicine Immunology and Allergy Humans [INFO]Computer Science [cs] 030212 general & internal medicine [MATH]Mathematics [math] Child Asthma Rhinitis upper airways business.industry medicine.disease 3. Good health respiratory tract diseases Asthmatic children Cross-Sectional Studies 030228 respiratory system Breath Tests Spirometry Child Preschool Pediatrics Perinatology and Child Health Exhaled nitric oxide Immunology Female business |
| Zdroj: | Journal of Asthma Journal of Asthma, Informa Healthcare, 2010, 47 (6), pp.604-608. ⟨10.3109/02770901003759402⟩ |
| ISSN: | 0277-0903 1532-4303 |
| Popis: | International audience; Background. The prevalence of rhinitis is high and frequently observed in association with asthma. Although the persistence of predisposing factors such as rhinitis is frequently observed in adults, this has not yet been confirmed in children. Aims. The aim of this present work is to show the relationship between rhinitis and asthma control in asthmatic children. Methods. The authors carried out a cross-sectional study by collecting clinical, spirometric, and fractional exhaled nitric oxide (FeNO) data in children aged from 4 to 17 years. Results. One hundred seventeen children were included. Asthma control was optimal in 37.6%, suboptimal in 55.5% and poor in 7.3% of cases. A 74.3% of children were atopic and 62.5% had symptoms 34 of rhinitis. Rhinitis was more frequent when control of asthma was worse (p = .0001). Age (p = .002), asthma control (p < .001), atopy (p = .001), and presence of rhinitis (p = .012) were significantly associated with FeNO. Conclusions. Our study confirms the strong relationship between upper airways and poor asthma control in the asthmatic child. Symptoms of rhinitis may be partly responsible for the increased fractional exhaled nitric oxide (FeNO) level, independently of the control of asthma. Evaluation of rhinitis should be included to improve assessment of asthma control in children |
| Databáze: | OpenAIRE |
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