A Trial of Chloroquine-Medicated Salt for Malaria Suppression in Uganda *
| Autor: | N. E. Wilks, S. A. Hall |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
Adult
Male Adolescent Population Administration Oral Drug resistance Sodium Chloride Toxicology Chloroquine Virology medicine Humans Standard test Uganda Child education Chloroquine resistance Alternative methods education.field_of_study business.industry Infant medicine.disease Malaria Infectious Diseases Child Preschool Immunology Female Parasitology business medicine.drug |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 16:429-442 |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.1967.16.429 |
| Popis: | Summary The distribution of chloroquine-medicated salt has been proposed as an alternative method of malaria eradication where insecticidal attack is not fully effective. The small trial described here was conducted in Uganda during 1964–66 to test the use of medicated salt among a changing population at two sugar estates. Salt containing 0.38% by weight chloroquine base was issued free, and the populations' experience compared with those not receiving medicated salt. Methods for the preparation and distribution of medicated salt are described. Satisfactory distribution led to significant reductions in crude parasite rates and reduction of morbidity to about one-third the level in nonrecipient workers, and to lower levels in women and children. Failure to achieve complete protection was attributed to administrative shortcomings, individual non-co-operation, or inadequate intake. The possibility of chloroquine resistance was excluded by use of a standard test procedure. The results of the trial were not encouraging for wider adoption, but could be justified for the situation in which it was tried. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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