Atopic dermatitis incidence and risk factors in young adults in Castellon (Spain): A prospective cohort study
| Autor: | Maria Rosario Pac-Sa, A. Arnedo-Pena, A. Vizcaino-Batllés, A. Artero-Civera, Maria Angeles Romeu-Garcia, C. Fenollosa-Amposta, J. Fabregat-Puerto, E. Silvestre-Silvester, Juan B. Bellido-Blasco, Noemi Meseguer-Ferrer, Joan Puig-Barberà, L. Segura-Navas, M.A. Dubón |
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| Rok vydání: | 2020 |
| Předmět: |
young adults
Adult Male Pulmonary and Respiratory Medicine Adolescent Immunology Population Dermatitis Atopic Young Adult symbols.namesake Sex Factors Risk Factors Surveys and Questionnaires Prevalence medicine risk factors Humans Immunology and Allergy Prospective Studies Poisson regression Family history Child Medical History Taking Prospective cohort study education Respiratory Tract Infections education.field_of_study atopic dermatitis business.industry Incidence Incidence (epidemiology) cohortIncidence Cohort General Medicine Atopic dermatitis medicine.disease Spain symbols Female business Demography Cohort study |
| Zdroj: | Repositori Universitat Jaume I Universitat Jaume I ALLERGOLOGIA ET IMMUNOPATHOLOGIA r-FISABIO. Repositorio Institucional de Producción Científica instname r-FISABIO: Repositorio Institucional de Producción Científica Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| ISSN: | 0301-0546 |
| DOI: | 10.1016/j.aller.2020.01.004 |
| Popis: | Introduction: There are few atopic dermatitis (AD) incidence cohort studies in young adults, the etiology of this disease remains obscure, and AD risk factors in adults are not well understood. The objective of this study was to estimate AD ten-year incidence and prevalence in a cohort of adolescent aged 14-16 at inception in Castellon province in Valencia Region, Spain and describe related risk factors. Material and methods: From 2002 to 2012, a population-based prospective cohort study was carried out. Questionnaires from the International Study of Asthma and Allergies in Childhood (ISAAC) were used with an additional questionnaire for related factors completed by participants and their parents, respectively, in 2002. In 2012 the same questionnaires were completed by the participants' through a telephone interview, and incidence and prevalence of AD were estimated. Directed acyclic graphs, Poisson regression and inverse probability weighted regression adjustment were used. Results: The participation rate was 79.5% (1435/1805) with AD lifetime prevalence of 34.9% and AD incidence of 13.5 per 1000 person years. Females presented higher prevalence and incidence than males. After adjustment significant risk factors were being female, history of asthma or allergic rhinitis, family history of AD, history of respiratory infections, history of bronchitis, history of pneumonia, history of sinusitis, and birthplace outside Castellon province. The highest AD population attributable risks were female, 30.3%, and history of respiratory infections 15.3%. Differences with AD childhood risk factors were found. Conclusions: AD incidence in our cohort was high and several risks factors were related to AD. (C) 2020 SEICAP. Published by Elsevier Espaa, S.L.U. All rights reserved. |
| Databáze: | OpenAIRE |
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