Whole-Saliva Fluoride Levels and Saturation Indices in 65+ Elderly during Use of Four Different Toothpaste Regimens

Autor:	Joan Lykkeaa, Mia Linding Ekstrand, Allan Bardow, Kim R. Ekstrand, Svante Twetman
Rok vydání:	2015
Předmět:	Male Toothbrushing Saliva business.product_category Saliva secretion Dentistry Dental Caries Oral hygiene Phosphates Monofluorophosphate chemistry.chemical_compound Fluorides Fluoride toothpaste Medicine Humans Whole saliva General Dentistry Aged Aged 80 and over Minerals Toothpaste business.industry Oral Hygiene Cariostatic Agents chemistry Sodium Fluoride Female business Fluoride Toothpastes
Zdroj:	Caries research. 49(5)
ISSN:	1421-976X
Popis:	Background: Elderly individuals suffering from subnormal saliva secretion combined with inadequate oral hygiene may develop rampant caries and caries in parts of the dentition not normally affected by caries if preventive measures are not undertaken. Such measures include elevating fluoride levels at the saliva/biofilm/tooth interface. Aim: To analyse whole-saliva fluoride levels and mineral saturation indices during different fluoride toothpaste regimens in home-living elderly. Materials and Methods: Whole saliva was collected from 27 subjects (7 males and 20 females, mean age 73.5 ± 6.1 years) at ten time points covering the whole day during five 2-week periods. During the first period, participants used their normal toothpaste without instructions (baseline). This was followed by TP1: 1,450-ppm NaF toothpaste; TP2: 1,450-ppm monofluorophosphate (MFP) toothpaste with addition of calcium; TP3: 5,000-ppm NaF toothpaste, and TP4: the same toothpaste with additional ‘smearing' of toothpaste on the teeth, twice daily. During TP1-TP4, the participants were instructed to brush 3 times per day using 1.5 g of toothpaste without rinsing. Results: Salivary fluoride levels increased with toothpaste fluoride content (p < 0.001), although major interindividual and intraindividual variations were observed. The highest fluoride values appeared in the morning and at night (p < 0.001). Saturation indices for calcium fluoride were affected by the fluoride content in pastes (p < 0.05). Concerning hydroxyapatite and fluorapatite, indices were highest with the MFP toothpaste and extra calcium (NS to p < 0.05). Conclusions: Use of a high-fluoride toothpaste resulted in significantly increased fluoride levels in whole saliva and mineral saturation indices were indeed influenced by choice of toothpaste.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e5f9dba652785332c9254dbfa4d6ae https://pubmed.ncbi.nlm.nih.gov/26278523 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.