Are pain-related fears mediators for reducing disability and pain in patients with complex regional pain syndrome type 1? An explorative analysis on pain exposure physical therapy
| Autor: | Maria W.G. Nijhuis-van der Sanden, Han Samwel, Frank P Klomp, Robert van Dongen, Jan Paul M. Frölke, Henk van de Meent, Karlijn J Barnhoorn, J. Bart Staal |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Strength training Psychological intervention lcsh:Medicine Pain Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] law.invention Pharmacotherapy Randomized controlled trial law Humans Medicine lcsh:Science Pain Measurement Multidisciplinary business.industry lcsh:R Fear Guideline Middle Aged Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3] medicine.disease Reflex Sympathetic Dystrophy Clinical trial Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10] Treatment Outcome Complex regional pain syndrome Physical therapy lcsh:Q Female Pain catastrophizing business Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 10, Iss 4, p e0123008 (2014) PLoS One, 10 PLoS One, 10, 4 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0123008 |
| Popis: | Contains fulltext : 156854.pdf (Publisher’s version ) (Open Access) OBJECTIVE: To investigate whether pain-related fears are mediators for reducing disability and pain in patients with Complex Regional Pain Syndrome type 1 when treating with Pain Exposure Physical Therapy. DESIGN: An explorative secondary analysis of a randomised controlled trial. PARTICIPANTS: Fifty-six patients with Complex Regional Pain Syndrome type 1. INTERVENTIONS: The experimental group received Pain Exposure Physical Therapy in a maximum of five treatment sessions; the control group received conventional treatment following the Dutch multidisciplinary guideline. OUTCOME MEASURES: Levels of disability, pain, and pain-related fears (fear-avoidance beliefs, pain catastrophizing, and kinesiophobia) were measured at baseline and after 3, 6, and 9 months follow-up. RESULTS: The experimental group had a significantly larger decrease in disability of 7.77 points (95% CI 1.09 to 14.45) and in pain of 1.83 points (95% CI 0.44 to 3.23) over nine months than the control group. The potential mediators pain-related fears decreased significantly in both groups, but there were no significant differences between groups, which indicated that there was no mediation. CONCLUSION: The reduction of pain-related fears was comparable in both groups. We found no indication that pain-related fears mediate the larger reduction of disability and pain in patients with Complex Regional Pain Syndrome type 1 treated with Pain Exposure Physical Therapy compared to conventional treatment. TRIAL REGISTRATION: International Clinical Trials Registry NCT00817128. |
| Databáze: | OpenAIRE |
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