Registry report of structural and functional cardiac abnormalities diagnosed by echocardiography in an asymptomatic population

Autor: Darlington O. Okonko, Amit K J Mandal, Donald R. J. Singer, Paul Highett-Smith, Apurva Bharucha, Constantinos G Missouris, Mohamed Al-Obaidi
Rok vydání: 2016
Předmět:
Zdroj: Postgraduate Medical Journal. 92:450-454
ISSN: 1469-0756
0032-5473
DOI: 10.1136/postgradmedj-2014-133001
Popis: Background The epidemiology of heart disease is changing, with rheumatic heart disease becoming less common but degenerative valve disorders, heart failure and atrial fibrillation (AF) increasing. Objective We sought to determine the prevalence of structural cardiac abnormalities in the apparently symptom-free adult population within our prospective echocardiography (echo) registry. Methods Our echo registry comprised echo studies and associated demographic and clinical data obtained prospectively from 362 consecutive asymptomatic subjects aged 50–74 years and without known heart disease referred between 2011 and 2012 from general practices in the South East of England. Results 221 echo abnormalities were detected in 178 (49%) subjects (46% men; mean (±SD) age 63.9±9.2 years; 98% Caucasian). A major abnormality was detected in seven subjects: four had a large secundum atrial septal defect, one had critical aortic stenosis, one severe mitral regurgitation and one features of hypertrophic cardiomyopathy. Twelve subjects had left ventricular systolic dysfunction with an ejection fraction (EF) Conclusions Unrecognised cardiac abnormalities are very common in middle-aged men and women with no overt symptoms. Echo offers the potential to identify the need for early intervention and treatment to improve cardiovascular outcomes.
Databáze: OpenAIRE