Human Papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women
Autor: | Aluísio Augusto Cotrim Segurado, Matsubara R, Maria Cristina Domingues da Silva Fink, Iara M. Linhares, Carretiero N, Das Dores Gb, Eluf J J, Cynthia L.M. Canto, Castelo A, José Eduardo Levi, Uip De |
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Jazyk: | angličtina |
Předmět: |
Cross-sectional study
lcsh:QR1-502 Uterine Cervical Neoplasms HIV Infections lcsh:Microbiology Risk Factors Prevalence Papillomaviridae Cervical cancer education.field_of_study biology Age Factors virus diseases Middle Aged viral load AIDS Infectious Diseases Female Viral load Brazil Microbiology (medical) Adult Adolescent Population cervical intraepithelial neoplasia Cervical intraepithelial neoplasia lcsh:Infectious and parasitic diseases Acquired immunodeficiency syndrome (AIDS) medicine Humans lcsh:RC109-216 Neoplasms Squamous Cell education Aged Vaginal Smears business.industry HIV-infected women Papillomavirus Infections Cancer HIV Human Papillomavirus medicine.disease biology.organism_classification Virology CD4 Lymphocyte Count Tumor Virus Infections DNA Viral business |
Zdroj: | Brazilian Journal of Infectious Diseases, Vol 6, Iss 3, Pp 129-134 Brazilian Journal of Infectious Diseases, Vol 6, Iss 3, Pp 129-134 (2002) Brazilian Journal of Infectious Diseases v.6 n.3 2002 Brazilian Journal of Infectious Diseases Brazilian Society of Infectious Diseases (BSID) instacron:BSID Brazilian Journal of Infectious Diseases, Volume: 6, Issue: 3, Pages: 129-134, Published: JUN 2002 |
ISSN: | 1678-4391 |
Popis: | HIV-infected women from S o Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD(4)(+) cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5%). Twenty (7.5%) women were infected by one or more low-risk viruses, 89 (33%) by one or more high-risk viruses, and 64 (24%) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19% of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD(4)/microL |
Databáze: | OpenAIRE |
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