Biological Properties of Essential Oils from
| Autor: | Jesus Simal-Gandara, Barbara Sawicka, Hamza Ouakouak, Naima Benchikha, Samir Begaa, Adel Benarfa, Mohammed Messaoudi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
2414.08 Procesos Microbianos
3309.03 Antioxidantes en Los Alimentos DPPH antioxidant activity Plant Science 01 natural sciences Article law.invention Borneol Candida tropicalis chemistry.chemical_compound Camphor law 2302.10 Aceites Esenciales chemical composition antitumor activity Food science essential oils Ecology Evolution Behavior and Systematics Essential oil ABTS antimicrobial activity Ecology biology 010405 organic chemistry Botany biology.organism_classification Thymus algeriensis Boiss 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry QK1-989 Camphene GC-MS Micrococcus luteus |
| Zdroj: | Plants Volume 10 Issue 4 Investigo. Repositorio Institucional de la Universidade de Vigo Universidade de Vigo (UVigo) Plants, Vol 10, Iss 786, p 786 (2021) |
| ISSN: | 2223-7747 |
| Popis: | This study describes the chemical composition, antitumor, antioxidant, and antimicrobial activities of the plant Thymus algeriensis Boiss. Essential oils (EOs) were collected in different periods (before, during, and after flowering stage) from the El-Guetfa region, M’sila, Algeria. The EOs extraction was achieved using three distinguishing techniques: hydro (Clevenger trap), steam, and microwave distillations, targeting different aerial parts of the plant (stems, flowers, and leaves). The EOs chemical components were estimated using GC-FID and GC-MS apparatuses. The resulting yield of the extracted oil was moderate and ranged between 0.84 and 1.53% (wt/vol). In total, eighty-five components were identified, in which the oxygenated monoterpenes family formed the main portion, starting from 40.56 up to 70.66%. The obtained essential oil was dominated by five major components that varied from low to quite moderate percentages: camphor (17.45–32.56%), borneol (11.16–22.2%), camphene (7.53–12.86%), 1.8-cineole (5.16–11.21%), and bornyl acetate (3.86–7.92%). The biological results of this oil pointed out that the EOs extracted from the leaves part exposed a weak radical scavenging activity afterward using two well-known antioxidant assays DPPH (IC50 = 8.37 mg/mL) and ABTS (10.84 mg/mL). Meanwhile, this oil presented strong inhibition activity against colon cancer cell line HCT116 (LC50 = 39.8 µg/mL) and a moderate inhibitory against hepatocellular cancer cells HePG2 (LC50 > 100 µg/mL). In addition, this oil antimicrobial activity was quite important against Micrococcus luteus (M. luteus), Staphylococcus aureus CIP 7625, Escherichia coli ATCC 10536, Saccharomyces cerevisiae ATCC 4226, Candida albicans IPA200, Candida tropicalis (Ct), and Candida glabrata (Cg) after using Amoxicillin and Itraconazole as references. |
| Databáze: | OpenAIRE |
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