Epidermolysis bullosa acquisita
| Autor: | Radha Mikkilineni, Jennifer A. Stein |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Epidermolysis bullosa acquisita
Pathology medicine.medical_specialty integumentary system medicine.diagnostic_test business.industry Autoantibody Dermatology General Medicine medicine.disease medicine.anatomical_structure Milia Biopsy Anchoring fibrils medicine business Direct fluorescent antibody Blood vessel Blistering disease |
| Zdroj: | Stein, Jennifer A; & Mikkilineni, Radha. (2007). Epidermolysis bullosa acquisita. Dermatology Online Journal, 13(1). Retrieved from: http://www.escholarship.org/uc/item/6222v7f3 |
| Popis: | A 29-year-old woman presented with 8 months of multiple vesicles, erosions, and milia on the dorsa of her hands and feet. Histopathologic examination demonstrated a subepidermal blister, with a paucity of eosinophils and a lack of blood vessel wall thickening or caterpillar bodies. A direct immunofluorescence test showed a linear deposit of IgG at the dermo-epidermal junction. These findings were consistent with a diagnosis of epidermolysis bullosa acquisita. This case is a classic example of this rare blistering disease, in which patients produce autoantibodies to collagen VII, which is the major component of the anchoring fibrils. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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