Robot-Assisted Radical Cystectomy for Nonmetastatic Urothelial Carcinoma of Urinary Bladder: A Comparison Between Intracorporeal Versus Extracorporeal Orthotopic Ileal Neobladder
| Autor: | Gabriele Cozzi, Michele Catellani, Antonio Brescia, Giovanni Cordima, Antonio Cioffi, Claudia Collà Ruvolo, A. Conti, Ottavio De Cobelli, Vincenzo Mirone, Matteo Ferro, Deliu Victor Matei, Ettore Di Trapani, Roberto Bianchi, Danilo Bottero, Stefano Luzzago, Francesco A. Mistretta, F. Verweij, Gennaro Musi |
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| Přispěvatelé: | Mistretta, F. A., Musi, G., Colla Ruvolo, C., Conti, A., Luzzago, S., Catellani, M., Di Trapani, E., Cozzi, G., Bianchi, R., Ferro, M., Cioffi, A., Cordima, G., Brescia, A., Verweij, F., Bottero, D., Matei, D. V., Mirone, V., De Cobelli, O. |
| Rok vydání: | 2021 |
| Předmět: |
robotic
medicine.medical_specialty Urology medicine.medical_treatment 030232 urology & nephrology complication Urinary Diversion Cystectomy Extracorporeal 03 medical and health sciences 0302 clinical medicine Robotic Surgical Procedures Humans Medicine Complication rate Retrospective Studies Urothelial carcinoma Urinary bladder business.industry Continent Urinary Reservoir continent urinary reservoir Robotics Treatment Outcome medicine.anatomical_structure Urinary Bladder Neoplasms 030220 oncology & carcinogenesis Neoplasm Recurrence Local business |
| Zdroj: | Journal of Endourology. 35:151-158 |
| ISSN: | 1557-900X 0892-7790 |
| DOI: | 10.1089/end.2020.0622 |
| Popis: | Introduction: To compare surgical, oncologic, functional outcomes and complication rate between intracorporeal neobladder (ICNB) and extracorporeal neobladder (ECNB) orthotopic ileal neobladder of robot-assisted radical cystectomy (RARC) in patients with nonmetastatic bladder carcinoma (BC). Materials and Methods: From 2014 to 2019, we prospectively collected and retrospectively analyzed 101 patients with nonmetastatic BC treated with RARC and ortothopic neobladder. Chi-squared test estimated differences in proportions of functional and oncologic outcomes. Multivariable logistic regression models (MLRMs) focused on overall, early (30 days from discharge) in ICNB vs ECNB. Results: Of all patients, 57 (56.4%) ICNB and 44 (43.6%) ECNB patients were identified. At least one complication occurred in 75.4% vs 72.7% in ICNB vs ECNB, respectively (p = 0.9). In MLRMs, focusing on complication rate, there was no statistically significant difference between ICNB vs ECNB for overall (p = 0.8), early (p = 0.6), and late complications (p = 0.8). No statistically significant differences were recorded for tumor relapse rate, cancer-specific and other cause mortality. No positive surgical margins were recorded in both groups. Daytime and nighttime continence recovery were 89.4% vs 87.1% (p = 1.0) and 63.8% vs 51.6% (p = 1.0) for ICNB vs ECNB. Potency recovery was 59.1% vs 54.3% (p = 0.5) for ICNB vs ECNB. Conclusions: No statistically significant differences in complication rate (overall, early, or late) were identified, when ICNB and ECNB were compared. Similarly, no statistically significant difference was found in oncologic and functional outcomes. |
| Databáze: | OpenAIRE |
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