Mechanism of hypocholesterolemic effect of oyster mushroom (Pleurotus ostreatus) in rats: reduction of cholesterol absorption and increase of plasma cholesterol removal
| Autor: | L. Kuniak, P. Bobek, L Ozdín |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Oyster animal structures Hypercholesterolemia Medicine (miscellaneous) Biochemistry Intestinal absorption Cholesterol Dietary Polyporaceae chemistry.chemical_compound Internal medicine biology.animal medicine Weaning Animals Food science Rats Wistar Triglycerides Mushroom biology Cholesterol Anticholesteremic Agents fungi food and beverages Half-life Metabolism biology.organism_classification Rats Endocrinology chemistry Intestinal Absorption Liver lipids (amino acids peptides and proteins) Pleurotus ostreatus Food Science Half-Life |
| Zdroj: | Zeitschrift fur Ernahrungswissenschaft. 33(1) |
| ISSN: | 0044-264X |
| Popis: | The content of cholesterol in the serum and liver of male Wistar rats fed, for the period of 8 weeks shortly after weaning, a diet containing 0.3% of cholesterol was reduced by 33 and 27% by the addition of 5% of dried oyster mushroom powder. Although the level of serum triacylglycerols was not affected by oyster mushroom, their content in liver of rats on mushroom diet was reduced by 41%. Very-low-density lipoproteins and low-density lipoproteins participated by 55 and 38%, respectively, in the total reduction of serum cholesterol. Cholesterol content in high-density lipoproteins was not significantly affected by oyster mushroom. Cholesterol absorption as determined by dual-isotope plasma ratio method was significantly reduced by 14% with oyster mushroom diet. Similarly, this diet increased by 42% the fractional catabolic rate of cholesterol determined by the analysis of decay curve of [4−14C]cholesterol. |
| Databáze: | OpenAIRE |
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