Mitral Valve Repair in Children Below Age 10 Years: Trouble or Success?
| Autor: | Nora Lang, Bernhard Voss, Benedikt Mayr, Keti Vitanova, Gertrud Goppel, Julie Cleuziou, Melchior Burri, Rüdiger Lange |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty medicine.medical_treatment Heart Valve Diseases 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Valve replacement Mitral valve Humans Medicine Effective treatment Cumulative incidence In patient Child Retrospective Studies Mitral regurgitation Mitral valve repair business.industry Operative mortality Age Factors Infant Newborn Infant digestive system diseases Surgery Survival Rate Treatment Outcome medicine.anatomical_structure 030228 respiratory system Child Preschool cardiovascular system Mitral Valve Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | The Annals of Thoracic Surgery. 110:2082-2087 |
| ISSN: | 0003-4975 |
| DOI: | 10.1016/j.athoracsur.2020.02.057 |
| Popis: | Background Mitral valve (MV) repair in children is challenging because of the broad spectrum of lesions and anticipated patient growth. The purpose of the study was to evaluate the outcome of MV repair in children below 10 years of age. Methods We reviewed all MV repair procedures performed in children below 10 years of age. Endpoints of the study were survival after MV repair and cumulative incidence of reoperation. Results MV repair was performed in 40 patients with congenital MV disease (MVD) and in 10 patients with acquired MVD. Median age at time of repair for congenital MVD was 1.2 years (range, 14 days to 9.8 years) and for acquired MVD 1.9 years (range, 10 days to 9.9 years). Indication for MV repair was mitral regurgitation in 31 congenital MVD patients (77.5%) and in all acquired MVD patients. In patients with congenital MVD operative mortality was 5% and late mortality was 10%. No deaths occurred in patients with acquired MVD. Patients with congenital mitral regurgitation showed a better, yet not significant, 6-year survival than patients with congenital mitral stenosis (85.3% ± 8.2% vs 60% ± 18.2%, P = .1). In patients with congenital MVD cumulative incidence of reoperation at 6 years was 38.6% ± 8.3%. Conclusions In children below 10 years of age, MV repair is an effective treatment option for MVD. However it often just delays the time to valve replacement. |
| Databáze: | OpenAIRE |
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