Mandibular prognathism attenuates brain blood flow induced by chewing
| Autor: | Takashi Oikawa, Satoshi Wada, Shun Akaike, Yoshiki Nakamura, Takuya Seko, Erika Ozawa, Hiroshi Tomonari, Masao Kumazawa, Hiroyuki Kanzaki, Tomomi Sudo, Yuko Yamada, Satoshi Okumura, Masumi Murakami |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Craniofacial orthodontics Silicones lcsh:Medicine Mandible Electromyography Masseter muscle 0302 clinical medicine Occlusion Tooth loss Medicine lcsh:Science Orthodontics Spectroscopy Near-Infrared Multidisciplinary medicine.diagnostic_test Brain Frontal Lobe Cerebral blood flow Cerebrovascular Circulation Prognathism Female medicine.symptom Muscle Contraction Muscle contraction Adult Inferior frontal gyrus Neuroimaging Brain imaging Article Young Adult 03 medical and health sciences Near-infrared spectroscopy Humans Mastication Masseter Muscle business.industry lcsh:R 030206 dentistry Cross-Sectional Studies Malocclusion Angle Class III Oxyhemoglobins Dementia lcsh:Q business Malocclusion 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-019-55553-5 |
| Popis: | Mastication is closely related to brain function. Animal experiments have revealed that tooth loss has a negative influence on brain function. Clinical studies also suggest that normal occlusion is an essential factor for favorable brain function. Mandibular prognathism (MP) usually results in occlusal dysfunction. However, the relationship between MP and brain function remains unclear. In the present study, we examined the relationship between MP and brain function by measuring brain blood flow (BBF). Seventeen subjects with normal occlusion (NORM) and 25 patients with MP participated in this study. The number of occlusal contacts were counted. Electromyography of the masseter muscles during clenching was also recorded. BBF was measured with non-invasive functional near-infrared spectroscopy during calculation task and chewing task. The number of the occlusal contacts and masseter muscle activity were lower in MP compared with NORM. The calculation task increased BBF in both groups. The chewing task also increased BBF in the inferior frontal gyrus in both groups, although the increase in MP was smaller than in NORM. We discovered that patients with MP exhibited a smaller increase in BBF at the inferior frontal gyrus during chewing as compared with NORM. As such, MP would negatively affect brain function. |
| Databáze: | OpenAIRE |
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