Saponins of Allium elburzense
| Popis souboru: | ELETTRONICO |
|---|---|
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/np0497752 |
| Přístupová URL adresa: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ba94bcc1624e0c7338af40a80b85e6 https://doi.org/10.1021/np0497752 |
| Rights: | CLOSED |
| Přírůstkové číslo: | edsair.doi.dedup.....55ba94bcc1624e0c7338af40a80b85e6 |
| Autor: | Behzad Zolfaghari, Virginia Lanzotti, S. Ebrahim Sajjadi, Elisa Barile |
| Přispěvatelé: | E., Barile, B., Zolfaghari, S. E., Sajjadi, Lanzotti, Virginia |
| Rok vydání: | 2004 |
| Předmět: |
Stereochemistry
Saponin Pharmaceutical Science Iran Mass spectrometry Plant Roots Allium Analytical Chemistry chemistry.chemical_compound Drug Discovery Spirostans Furans Nuclear Magnetic Resonance Biomolecular Pharmacology chemistry.chemical_classification Plants Medicinal Molecular Structure biology Chemistry Organic Chemistry Absolute configuration Glycoside Stereoisomerism Saponins biology.organism_classification Complementary and alternative medicine Phytochemical Aldose Molecular Medicine Hemiacetal |
| Zdroj: | Journal of Natural Products. 67:2037-2042 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/np0497752 |
| Popis: | A phytochemical investigation of the bulbs of Allium elburzense has been undertaken, leading to the isolation of 13 furostanol and spirostanol saponins, eight of which are new, namely, elburzensosides A1/A2 (1a/1b), B1/B2 (2a/2b), C1/C2 (3a/3b), and D1/D2 (4a/4b). On the basis of spectroscopic analysis, mainly 2D NMR and mass spectrometry, and chemical methods, the structures of the new compounds were determined as furost-2alpha,3beta,5alpha,6beta,22alpha-pentol 3-O-beta-D-glucopyranosyl 26-O-beta-D-glucopyranoside (1a), furost-2alpha,3beta,5alpha,6beta,22alpha-pentol 3-O-beta-D-glucopyranosyl-(1-->4)-O-beta-D-glucopyranosyl] 26-O-beta-D-glucopyranoside (2a), furost-2alpha,3beta,5alpha,22alpha-tetrol 3-O-beta-D-glucopyranosyl 26-O-beta-D-glucopyranoside (3a), and furost-2alpha,3beta,5alpha,22alpha-tetrol 3-O-[beta-D-xylopyranosyl-(1-->3)-O-beta-D-glueopyranosyl-(1-->4)-O-beta -D-galactopyranosyl 26-O-beta-D-glucopyranoside (4a), and the corresponding epimers at position 22 (1b-4b). Along with these compounds we have isolated the corresponding 22-O-methyl derivatives that we consider extraction artifacts. All the new elburzensosides A1/A2-D1/D2 possess as a common structural feature an OH-5alpha that is rare among furostanol saponins. The reported compounds have been isolated in large amounts, and this makes A. elburzense a prolific producer of saponins of the furostanol and spirostanol types. |
| Databáze: | OpenAIRE |
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