Correlation Analysis of Conventional Ultrasound Characteristics and Strain Elastography with Ki-67 Status in Breast Cancer
| Autor: | Jianqiang Fang, Binyu Zhang, Weian Zhao, Hao Wang, Cui Pu, Qing Li |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Strain elastography medicine.medical_specialty Acoustics and Ultrasonics Biophysics Breast Neoplasms Conventional ultrasound Logistic regression 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences 0302 clinical medicine Breast cancer Biopsy Humans Medicine Radiology Nuclear Medicine and imaging Correlation of Data Aged Retrospective Studies Aged 80 and over Radiological and Ultrasound Technology medicine.diagnostic_test biology business.industry Middle Aged medicine.disease Ki-67 Antigen 030220 oncology & carcinogenesis Ki-67 Correlation analysis biology.protein Elasticity Imaging Techniques Female Ultrasonography Mammary Radiology business |
| Zdroj: | Ultrasound in Medicine & Biology. 46:2972-2978 |
| ISSN: | 0301-5629 |
| DOI: | 10.1016/j.ultrasmedbio.2020.06.024 |
| Popis: | Our objectives were to measure the relationships between conventional ultrasound features, strain elastography in breast cancer and Ki-67 index and to identify parameters that predict Ki-67 index. We included 181 lesions of 178 patients who underwent surgery for breast cancer at Xianyang Central Hospital. In multivariate logistic regression analysis, strain elastography and axillary-node metastasis showed significant Ki-67 index values; the overall theoretical prediction percentage correct was 75.7%. Strain elastography showed that the median Ki-67 index in the hard group was higher than that in the soft group, and the Ki-67 index increased with increasing elasticity score. This finding may guide ultrasound-guided breast tumor biopsy for selection of puncture regions. The combined use of the Ki-67 index for strain-elastography prediction and puncture-biopsy pathology reports may increase the accuracy of clinical treatment. |
| Databáze: | OpenAIRE |
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