Should Omentectomy Be a Part of Surgical Staging in Patients with Endometrioid Adenocarcinoma of the Uterine Corpus?
| Autor: | Cuneyt Ongut, Ceyhun Numanoglu, Volkan Ulker, Ozgur Akbayir, Alpaslan Akyol, Aysun Fendal Tunca, Adnan Erim |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Oncology medicine.medical_specialty endocrine system diseases Surgical staging Adenocarcinoma Internal medicine medicine Humans Endometrioid adenocarcinoma In patient neoplasms Peritoneal Neoplasms Aged Neoplasm Staging Aged 80 and over business.industry Obstetrics and Gynecology Middle Aged female genital diseases and pregnancy complications Endometrial Neoplasms Omentectomy Logistic Models Reproductive Medicine Uterine corpus Multivariate Analysis Omental metastasis Female Radiology business Carcinoma Endometrioid Omentum |
| Zdroj: | Gynecologic and Obstetric Investigation. 77:58-63 |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000357270 |
| Popis: | Background: The purpose of the study was to determine the prevalence of omental metastasis in endometrioid adenocarcinoma and to correlate risk variables with this spread. Methods: A retrospective analysis of patients with endometrioid adenocarcinoma who underwent omentectomy in addition to staging laparotomy was performed. Results: Omental metastases were noted in 11 of the 322 patients with endometrioid adenocarcinoma (3.4%). Multivariate analyses showed that there was a significant correlation between omental metastasis and positive peritoneal cytology, adnexal involvement, and grade 3 tumor (p = 0.028, p = 0.001, and p = 0.01, respectively). There was no statistical relationship between omental metastasis and lymphovascular space involvement, deep myometrial invasion, and lymph node metastasis (p = 0.087, p = 0.97, and p = 0.92, respectively). Conclusion: Grade 3 endometrioid adenocarcinomas, especially those that are complicated by deep myometrial invasion, have a pattern of intra-abdominal spread similar to more aggressive endometrial cancers, with frequent involvement of the omentum. Overall, we conclude that 37.5% (3/8) of patients who had a grade 3 tumor and omental metastasis stage IV disease would have been missed if a staging operation similar to that employed for ovarian cancer had not been performed. |
| Databáze: | OpenAIRE |
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